How many calories are burned running? It depends on the distance ran, speed and the weight of the person. Running burns twice the amount burnt by walking. Running we jump and move legs up and down hence it reduces tremendous amount of calories compared to walking. It is the best treatment for obesity and it should be a year around activity. Running a mile we can reduce .75 times multiplied by the weight of the person (lbs). Men burn approximately 124 calories, women 105 calories according to a study.